Inorganic Chemistry

Organometallic Chemistry

What is cisplatin, and how does it help to fight cancer?

Cisplatin is a platinum-based compound (see structure below) that reacts with DNA causing it to crosslink, eventually leading to programmed cell death, also known as apoptosis. Cisplatin was the first in a class of platinum containing anticancer drugs. It has been used to fight several types of cancer and is particularly effective against testicular cancer.



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