Yes, James and Lucretia had seven children, five of whom survived to adulthood: Harry Augustus, James Rudolph, Mary, Irvin, and Abram. Harry Augustus Garfield became a lawyer and a law professor at Western Reserve University. He then taught at Princeton University and became the president of Williams College. James Rudolph also became a lawyer, graduating with his older brother at Columbia Law School. James served in the Ohio state Senate and later served as secretary of the interior under President Theodore Roosevelt. Mary married Joseph Stanley-Brown, who became an investment banker. Irvin McDowell Garfield also graduated from Columbia Law School and started a successful law firm in Boston. Abram Garfield went to the Massachusetts Institute of Technology and became a respected architect.