Brain and Behavior

Motor Behavior and Intentional Action

How does psychiatric medication affect extrapyramidal neurons?

Antipsychotic medication can disrupt the function of extrapyramidal neurons. This can result in disfiguring side effects, such as tardive dyskinesia, a syndrome characterized by tremors in the extremities and facial muscles. The atypical antipsychotics, a new class of medication, have now become popular because they produce fewer extrapyramidal side effects (e.g., restlessness, tremor, and muscular stiffness).