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Biology

DNA, RNA, and Chromosomes

What is the law of complementary base pairing?

The law of complementary base pairing refers to the pairing of nitrogenous bases in a specific manner: purines pair with pyrimidines. More specifically, adenine must always pair with thymine, and guanine must always pair with cytosine. The basis of this law came from the data obtained by Edwin Chargaff (1905–2002) and is known as Chargaff’s law, or rule.



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