Muscular System

Muscle Structure

What is dystrophin and how is it related to muscular dystrophy?

A muscle cell is packed with filaments of actin and myosin. Less abundant, but no less important, is a protein called dystrophin. It literally holds skeletal muscle cells together by linking actin in the cell to glycoproteins (called dystrophinassociated glycoproteins, or DAGs) that are part of the cell membrane.


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